Suppose that a rod-like DNA molecule of length 250 nm undergoes a conformational change

Chapter 19, Problem 19.25

(choose chapter or problem)

Suppose that a rod-like DNA molecule of length 250 nm undergoes a conformational change to a closed-circular (cc) form. (a) Use the information in 19.24 and an incident wavelength = 488 nm to calculate the ratio of scattering intensities by each of these conformations, Irod/Icc, when = 20, 45, and 90. (b) Suppose that you wish to use light scattering as a technique for the study of conformational changes in DNA molecules. Based on your answer to part (a), at which angle would you conduct the experiments? Justify your choice.

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