Ethylene glycol 1HOCH2CH2OH2 is a major component of antifreeze. If ingested, it is

Chapter 0, Problem 16.55

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Ethylene glycol \(\left(\mathrm{HO}-\mathrm{CH}_{2}-\mathrm{CH}_{2}-\mathrm{OH}\right)\) is a major component of antifreeze. If ingested, it is first converted to

\(\mathrm{HOOC}-\mathrm{CHO}\) (oxoethanoic acid) and then to

\(\mathrm{HOOC}-\mathrm{COOH}\) (oxalic acid), which is toxic. (16.5, 16.6)

a. What class of enzyme catalyzes the reactions described?

b. The treatment for the ingestion of ethylene glycol is an intravenous solution of ethanol. How might this help prevent toxic levels of oxalic acid in the body?

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