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The enolate of a ketone can be treated with an ester to

Chapter 22, Problem 22.9

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QUESTION:

The enolate of a ketone can be treated with an ester to give a diketone. Draw a mechanism for this Claisen-like reaction and explain why an acid source is required after the reaction is complete. O O O 1) LDA 2) OEt O 3) H3O+

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QUESTION:

The enolate of a ketone can be treated with an ester to give a diketone. Draw a mechanism for this Claisen-like reaction and explain why an acid source is required after the reaction is complete. O O O 1) LDA 2) OEt O 3) H3O+

ANSWER:

Step 1 of 3

This exercise tells us that the enolate of a ketone can be treated with an ester to give a diketone.

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