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Decoding Histones: How They Organize & Interact with DNA in Our Cells

Chapter 0, Problem 4–2

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QUESTION:

Which statements are true? Explain why or why not.

The four core histones are relatively small proteins with a very high proportion of positively charged amino acids; the positive charge helps the histones bind tightly to DNA, regardless of its nucleotide sequence.

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QUESTION:

Which statements are true? Explain why or why not.

The four core histones are relatively small proteins with a very high proportion of positively charged amino acids; the positive charge helps the histones bind tightly to DNA, regardless of its nucleotide sequence.

ANSWER:

Step 1 of 2

The histone protein has a high concentration of positively charged amino acids, such as lysine. This positive charge of histone proteins interacts with the negatively charged DNA. The DNA is found to be negatively charged because of the presence of a phosphate group in the DNA molecule. A phosphodiester bond is found between the two nucleotides of DNA.

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Decoding Histones: How They Organize & Interact with DNA in Our Cells
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Unravel the intricate relationship between histones and DNA. Learn how histones maintain DNA structure within the cell nucleus and understand the significance of charge attractions in DNA-histone binding.


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