Why is the conversion of fructose-6-phosphate to fructose-1, 6-bisphosphate sometimes called the “committed step” of glycolysis?

Chapter 23, Problem 23.17

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QUESTION: Why is the conversion of fructose-6-phosphate to fructose-1, 6-bisphosphate sometimes called the “committed step” of glycolysis?

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QUESTION: Why is the conversion of fructose-6-phosphate to fructose-1, 6-bisphosphate sometimes called the “committed step” of glycolysis?

ANSWER:

Step 1 of 3

Glycolysis, from the name itself, is the breaking down of glucose, with the help of enzymes, into pyruvic acid. It is a type of catabolic process in which energy is released.

Glycolysis involves two major phases, i.e., priming phase and pay off phase.

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