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Primary amines can also be prepared by the reaction of an

Chapter 16, Problem 45P

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QUESTION:

Primary amines can also be prepared by the reaction of an alkyl halide with azide ion, followed by catalytic hydrogenation. What advantage do this method and the Gabriel synthesis have over

the synthesis of a primary amine using an alkyl halide and ammonia?

Questions & Answers

QUESTION:

Primary amines can also be prepared by the reaction of an alkyl halide with azide ion, followed by catalytic hydrogenation. What advantage do this method and the Gabriel synthesis have over

the synthesis of a primary amine using an alkyl halide and ammonia?

ANSWER:

Solution 45P

When alkyl halide reacts with ammonia

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