In the biological and physical sciences, a common model

Chapter 11, Problem 65E

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QUESTION:

Problem 65E

In the biological and physical sciences, a common model for proportional growth over time is

E ( Y ) = 1 − e−βt ,

where Y denotes a proportion and t denotes time. Y might represent the proportion of eggs that hatch, the proportion of an organism filled with diseased cells, the proportion of patients reacting to a drug, or the proportion of a liquid that has passed through a porous medium. With n observations of the form (yi , ti ), outline how you would estimate and then form a confidence interval for β.

Questions & Answers

QUESTION:

Problem 65E

In the biological and physical sciences, a common model for proportional growth over time is

E ( Y ) = 1 − e−βt ,

where Y denotes a proportion and t denotes time. Y might represent the proportion of eggs that hatch, the proportion of an organism filled with diseased cells, the proportion of patients reacting to a drug, or the proportion of a liquid that has passed through a porous medium. With n observations of the form (yi , ti ), outline how you would estimate and then form a confidence interval for β.

ANSWER:

Step 1 of 6

In this exercise we have the following model:

According to this we have:

because

To estimate the parameter  by the method of least squares we can use the following linear model:

where

According to this, in this exercise we have:

where  is a random variable with  and .

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