For most ketones, hydrate formation is unfavorable, because the equilibrium favors the

Chapter 20, Problem 20.7

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For most ketones, hydrate formation is unfavorable, because the equilibrium favors the ketone rather than the hydrate. However, the equilibrium for hydration of hexafluoroacetone favors formation of the hydrate: Provide a plausible explanation for this observation. + H2O O F3C CF3 3CF CF3 HO OH > 99.99%

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