Solution Found!
Answer: Starting with benzene and using any other reagents
Chapter 19, Problem 19.75(choose chapter or problem)
Starting with benzene and using any other reagents of your choice, design a synthesis for each of the following compounds. Each compound has a Br and one other substituent that we did not learn how to install. In each case, you will need to choose one of the substituents that we learned in this chapter and then modify that substituent using reactions from previous chapters. Be careful to consider the order of events in each case. Br OH (a) (b) Br
Questions & Answers
QUESTION:
Starting with benzene and using any other reagents of your choice, design a synthesis for each of the following compounds. Each compound has a Br and one other substituent that we did not learn how to install. In each case, you will need to choose one of the substituents that we learned in this chapter and then modify that substituent using reactions from previous chapters. Be careful to consider the order of events in each case. Br OH (a) (b) Br
ANSWER:Step 1 of 6
(a) Synthesis of 2-(3-bromophenyl)propan-2-ol:
Benzene reacts with acetyl chloride in the presence of aluminum chloride to form acetophenone. This reaction is known as Friedel-Crafts acylation.
