In Problems 18, solve each pure-time differential equation. dy dx = x + sin x, where y0 = 0 for x0 = 0
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Textbook Solutions for Calculus For Biology and Medicine (Calculus for Life Sciences Series)
Question
Selection at a Single Locus We consider one locus with two alleles, A1 and A2, in a randomly mating diploid population. That is, each individual in the population is either of type A1A1, A1A2, or A2A2.We denote by p(t) the frequency of the A1 allele and by q(t) the frequency of the A2 allele in the population at time t. Note that p(t)+q(t) = 1.We denote the fitness of the Ai Aj type by wi j and assume that w11 = 1, w12 = 1s/2, and w22 = 1s, where s is a nonnegative constant less than or equal to 1. That is, the fitness of the heterozygote A1A2 is halfway between the fitness of the two homozygotes, and the type A1A1 is the fittest. If s is small, we can show that, approximately, dp dt = 1 2 sp(1 p) with p(0) = p0 (8.49) (a) Use separation of variables and partial fractions to find the solution of (8.49). (b) Suppose p0 = 0.1 and s = 0.01; how long will take until p(t) = 0.5? (c) Find limt p(t). Explain in words what this limit means.
Solution
The first step in solving 8.1 problem number 43 trying to solve the problem we have to refer to the textbook question: Selection at a Single Locus We consider one locus with two alleles, A1 and A2, in a randomly mating diploid population. That is, each individual in the population is either of type A1A1, A1A2, or A2A2.We denote by p(t) the frequency of the A1 allele and by q(t) the frequency of the A2 allele in the population at time t. Note that p(t)+q(t) = 1.We denote the fitness of the Ai Aj type by wi j and assume that w11 = 1, w12 = 1s/2, and w22 = 1s, where s is a nonnegative constant less than or equal to 1. That is, the fitness of the heterozygote A1A2 is halfway between the fitness of the two homozygotes, and the type A1A1 is the fittest. If s is small, we can show that, approximately, dp dt = 1 2 sp(1 p) with p(0) = p0 (8.49) (a) Use separation of variables and partial fractions to find the solution of (8.49). (b) Suppose p0 = 0.1 and s = 0.01; how long will take until p(t) = 0.5? (c) Find limt p(t). Explain in words what this limit means.
From the textbook chapter Solving Differential Equations you will find a few key concepts needed to solve this.
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