Solution Found!
Propose a mechanism for the following transformation: O O
Chapter 13, Problem 13.58(choose chapter or problem)
QUESTION:
Propose a mechanism for the following transformation: O O O O HO OH 1) Excess MeMgBr 2) H2O
Questions & Answers
QUESTION:
Propose a mechanism for the following transformation: O O O O HO OH 1) Excess MeMgBr 2) H2O
ANSWER:Step 1 of 7
Mechanism:
In the first step, the polarizable anion donates a hydride anion to the electrophilic carbon of one of the carbonyl carbons. Regeneration of the double bond kicks off an alkoxide leaving group.