The following drugs are synthesized using the methods in this chapter and in previous chapters. Devise a synthesis for each, starting with any compounds containing no more than six carbon atoms.
(a) Phenacetin, used with aspirin and caffeine in pain-relief medications.
(b) Methamphetamine, once considered a safe diet pill, but now known to be addictive and destructive to brain tissue.
(c) Dopamine, one of the neurotransmitters in the brain. Parkinson’s disease is thought to result from a dopamine deficiency.
\(\mathrm{CH}_{3} \mathrm{CH}_{2} \mathrm{O}\)
\(N H-C-C H_{3}\)
\(\mathrm{NHCH}_{3}\)
\(\mathrm{CH}_{2}-\mathrm{CH}-\mathrm{CH}_{3}\)
\(\mathrm{CH}_{2} \mathrm{CH}_{2} \mathrm{NH}_{2}\)
Equation transcription:
Text transcription:
{CH}{3}{CH}{2}{O}
N H-C-C H{3}
{NHCH}{3}
{CH}{2}-{CH}-{CH}{3}
{CH}{2}{CH}{2}{NH}{2}
Solution 40SP
(a) The synthesis of Phenacetin is given below -
(b) The synthesis of Methamphetamine is given below -
(c) The synthesis of dopamine is given below -