Solution: Phosphate buffers are important in regulating the
Chapter 8, Problem 8.47(choose chapter or problem)
Phosphate buffers are important in regulating the pH of intracellular fluids at pH values generally between 7.1 and 7.2. a. What is the concentration ratio of H2PO4 2 to HPO4 22 in intracellular fluid at pH 5 7.15? H2PO4 2(aq) 34 HPO4 22(aq) 1 H1(aq) Ka 5 6.2 3 1028 b. Why is a buffer composed of H3PO4 and H2PO4 2 ineffective in buffering the pH of intracellular fluid? H3PO4(aq) 34 H2PO4 2(aq) 1 H1(aq) Ka 5 7.5 3 1023
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